One of the questions Dr. Mejia gets asked alot is “Does Rogaine Work?” The answer is yes. Rogaine is an FDA approved product which contains minoxidil. Minoxidil is an ingredient that has been used for many years that has shown clinical growth in hair follicles.
Non-surgical hair growth products are becoming increasingly more popular. The keys for effectively treating hair loss are a proper diagnosis by an expert, early intervention and proper education for all of the non-surgical and surgical hair loss solutions.
We offer choices for treating your thinning hair or hair loss:
Propecia or Finasteride: These are oral medications that are for men. It comes in 5mg tablets, so for men, they should be quartered and taken once a day. It is only used in women who cannot get pregnant due to birth defects; therefore the tablets should be halved and taken once a day.
Spironolactone: (women only) This medication is for non childbearing women. It is a tablet and dosages range from 50-100mg twice a day. The medication is a potassium sparing diuretic but functions as an anti-androgen.
Rogaine or Minoxidil: The topical solutions come in 2% for women and 5% for men. They are to be used twice a day to scalp to reactivate your hair’s natural growth cycle by reinvigorating hair follicles that are shrunken due to hereditary hair loss.
The active ingredient in ROGAINE® products, minoxidil, reactivates your hair’s natural growth cycle by reinvigorating hair follicles that are shrunken due to hereditary hair loss. Over time, ROGAINE® products will reduce your hair loss and regrow natural, thicker-looking hair.
PRP/ACell: The newest technology to be used off label to stimulate follicular growth. Effective in both men and women. It is your own blood platelets which contain many growth factors, are injected into the scalp. All these stem cells and growth factors may reactivate the hair follicle thus stimulating hair growth.
The Laser Light Comb: Used three times a week for 8-15 minutes, this low level laser treatment may help stimulate hair growth.
Capillus Portable Low Level Laser Therapy Device: Treatment option for male/female pattern hair loss that emits low level laser to the treatment to the scalp in an effort to stimulate and improve the quality of hair. Recommended use is 30min 3x a week.
There is a new treatment to prevent ongoing hair loss. Prostaglandin or PGD2 is now thought to play a significant role in the development of Baldness.
Researchers and dermatologists Dr. Luis Garza and Dr. George Cotsarelis of the University of Pennsylvania recently identified a form of prostaglandin, or PGD2, in both mice and men scalp areas where baldness exists. This gives hope that the ability to block the action of PGD2 or its recently identified targeted receptor, GPR44, early in the process of hair loss could prevent or stop hair loss altogether.
In a language both you and I can understand, this means no more male pattern baldness and possibly no more female pattern hair loss.
While the study tested the hair loss causing effects of prostaglandin on the bald areas of mice and men’s heads, future studies may indicate a similar effect in women.
Currently approved therapies for hair loss consist of an orally taken once-a-day tablet called Propecia or Finasteride combined with the topical solutions Rogaine or Minoxidil which is applied to the scalp twice a day as a liquid or foam. Finasteride blocks testosterone from being converted into dihidrotestorone, which has been found to play a significant role in male pattern baldness. Rogaine or minoxidil reinvigorates the hair follicle to prevent it from shrinking or miniaturizing.
The exact mechanism through which dihidrotestorone causes male hair loss is unclear. However, with this key development, we might soon see topical solutions of prostaglandin inhibitors applied to scalps to stop the balding process.
Will it work better than minoxidil or finasteride?
This is not clear yet, but test results are certainly promising. Current studies are testing the effectiveness of topical prostaglandin inhibitors. Test results suggest they work but before we can use prostaglandin inhibitors to treat baldness they must pass tests for safety and efficacy standards. Though even before the safety tests have been completed, we will likely see an explosion of topically applied products claiming to block prostaglandins without full scientific testing of whether those products actually work.
Not all prostaglandins are alike. This study specifically looks at the PGD2 pathway coupled with the GPR-44 receptor but not the PGD2 receptor 1 (PTGDR). Consequently it is necessary to test the right topical product on the pathway described. While studies were done in mice and men, we can not jump to the conclusion that any known substance that has the ability to block prostglandins will actually penetrate through the scalp and get into the hair follicle at the cellular level to block prostaglandin D2 in the right concentration to get the action described in this study.
So buyer beware of any future topical product claims. There is new hope in the horizon with this study for gene therapy and possibly the ability for directed gene therapy to completely stop the balding process. Time will tell.
Kudos to Dr. Garza and Cotsarelis for their research and dedication to combating hair loss.
Dr. Mejia recently attended the American Society of Dermatologic Meeting in Orlando, FL. This article was featured on January 6, 2011 in Internal Medicine News with embedded video shown below.
Natural Hair Transplant Results are expected with the advanced procedures Dr. Mejia utilizes in his office. Hair transplant patients should expect that after undergoing the hair surgery, a friend or colleague wouldn’t even notice a hair surgery took place. Fuller denser hair is possible with natural results.
Dr. Mejia was interviewed by NBC’s channel 5 news. We seem to have an endless fascination with hair. Remember in the 60s and 70s, there was even a Broadway play about it called “hair.” But what happens when that long, beautiful hair falls out, and you’re bald?
Question asked in the interview: If you have hair replacement surgery, will it actually grow in the place that it fell out?
Well, some people have surgery to put it back on! How does it work? Good question! We’re pretty much a society of “anything goes” when it comes to hairstyles and hair color. In some cases, there’s *no* hair involved. And that’s what we’re focusing on today: that dome that lost its cover. more specifically, those who want to get it back through hair transplant surgery.
Sometimes you get a good question that just makes a lot of sense. After all, if what was there fell out in the first place, what makes you think a “transplanted” hair follicle is going to grow? Good question!” [Read more…]